After upgrading Ubuntu 16.04 LTS to 17.10, I couldn’t launch Chrome by searching with the Super key (which is called Gnome Shell Search now). Not Chromium mind you, but google-chrome-stable. Even after re-installing, it wouldn’t appear in the search results despite having it’s icon on the dock like every other app. After poking around I noticed this OnlyShowIn=Unity line looked suspicious considering the switch from Unity to Gnome, and commenting it out fixed it, no reboot necessary.
~/.local/share/applications/google-chrome.desktop [Desktop Entry] Encoding=UTF-8 Version=1.0 Type=Application Name=Chrome - Google Chrome Icon=google-chrome Path=/home/matt/Downloads Exec=/opt/google/chrome/chrome StartupNotify=false StartupWMClass=google-chrome #OnlyShowIn=Unity; X-UnityGenerated=true